重組人CD3E蛋白/Recombinant human CD3E protein, C-His (HEK293)說明書-分析方法-資訊-生物在線

重組人CD3E蛋白/Recombinant human CD3E protein, C-His (HEK293)說明書

作者:上海鈺博生物科技有限公司 2023-03-30T00:00 (訪問量:1414)

?Recombinant human CD3E protein, C-His (HEK293)

重組人CD3E蛋白

英文名稱 Recombinant human CD3E protein, C-His (HEK293)
中文名稱 重組人CD3E蛋白
別????名 CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE; Recombinant human CD3E protein, C-His (HEK293)??
理論分子量 12.69kDa
檢測分子量 20-23 kDa
性????狀 Liquid
濃????度 >0.5 mg/ml
物????種 Human
序????列 1-126/207
純????度 >90% as determined by SDS-PAGE
純化方法 AC
內毒素 Not analyzed
表達系統 HEK293 cell
活性 Not tested
標簽 C-His
緩?沖?液 Supplied as solution form in PBS or lyophilized from PBS (pH=7.4).
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2

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