產品介紹
BioXcell InVivoPlus anti-mouse Ly6G 1A8單克隆抗體與小鼠Ly6G反應。Ly6G分子量為21-25kDa,是GPI錨定的細胞表面蛋白Ly-6超家族的成員,在細胞信號傳導和細胞粘附中發揮作用。Ly6G在發育過程中由骨髓譜系中的細胞(包括單核細胞、巨噬細胞、粒細胞和嗜中性粒細胞)差異表達。單核細胞通常在發育過程中瞬時表達Ly6G,而成熟的粒細胞和外周嗜中性粒細胞保持表達,使Ly6G成為這些群體的良好細胞表面標志物。與BioXcell RB6-8C5抗體不同,1A8抗體與小鼠Ly6G特異性反應,而與Ly6C沒有交叉反應性的報道。
產品詳情
|
產品名稱 |
InVivoPlus anti-mouse Ly6G |
|
產品貨號 |
BP0075-1 |
|
產品規格 |
5/25/50/100mg |
|
反應種屬 |
Mouse |
|
克隆號 |
1A8 |
|
同種型 |
Rat IgG2a, κ |
|
免疫原 |
EL4J cells transfected with Ly6G |
|
實驗應用 |
in vivo neutrophil depletion in vivo MDSC depletion Immunofluorescence Immunohistochemistry (paraffin) Immunohistochemistry (frozen) Flow cytometry |
|
產品形式 |
PBS, pH 7.0,Contains no stabilizers or preservatives |
|
純度 |
>95%, Determined by SDS-PAGE |
|
聚合 |
<5%, Determined by SEC |
|
無菌處理 |
0.2 μm filtration |
|
純化方式 |
Protein G |
|
RRID |
AB_1107721 |
|
分子量 |
150 kDa |
|
小鼠病原檢測 |
Ectromelia/Mousepox Virus: Negative Hantavirus: Negative K Virus: Negative Lactate Dehydrogenase-Elevating Virus: Negative Lymphocytic Choriomeningitis virus: Negative Mouse Adenovirus: Negative Mouse Cytomegalovirus: Negative Mouse Hepatitis Virus: Negative Mouse Minute Virus: Negative Mouse Norovirus: Negative Mouse Parvovirus: Negative Mouse Rotavirus: Negative Mycoplasma Pulmonis: Negative Pneumonia Virus of Mice: Negative Polyoma Virus: Negative Reovirus Screen: Negative Sendai Virus: Negative Theiler’s Murine Encephalomyelitis: Negative |
|
保存條件 |
抗體原液保存在4°C,不能冷凍保存。 |
|
推薦同型對照 |
InVivoPlus rat IgG2a isotype control, anti-trinitrophenol(貨號BP0089) |
|
推薦抗體稀釋液 |
InVivoPure pH 7.0 Dilution Buffer(貨號IP0070) |
為什么選擇InVivoPlus抗體?
InVivoPlus級別的產品內毒素含量更低,經過多種實驗驗證,更適合用于體內實驗研究

該產品自上市已被多篇SCI文獻引用,品質有保證,以下是部分已發表的文獻引用:
|
應用 |
文章 |
|
體內中性粒細胞耗竭 (in vivo neutrophil depletion) |
1. Davis, R. W. t., et al. (2018). 'Luminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy' Photochem Photobiol . 2. Moynihan, K. D., et al. (2016). 'Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses' Nat Med. doi : 10.1038/nm.4200. 3. Conde, P., et al. (2015). 'DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance' Immunity 42(6): 1143-1158. 4. Griseri, T., et al. (2015). 'Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis' Immunity 43(1): 187-199. 5. Yamada, D. H., et al. (2015). 'Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection' Immunity 42(2): 379-390. 6. Ellis, G. T., et al. (2015). 'TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection' EMBO Rep 16(9): 1203-1218. 7. Deshmukh, H. S., et al. (2014). 'The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice' Nat Med 20(5): 524-530. |
|
體內中性粒細胞耗竭、流式細胞術、免疫組化石蠟切片(in vivo neutrophil depletion, Flow Cytometry, Immunohistochemistry (paraffin)) |
Coffelt, S. B., et al. (2015). 'IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis' Nature 522(7556): 345-348. |
|
體內中性粒細胞耗竭、流式細胞術、免疫組化石蠟切片、免疫組化冰凍切片(in vivo neutrophil depletion, Flow Cytometry, Immunohistochemistry (paraffin), Immunohistochemistry (frozen)) |
欣博盛生物科技有限公司 商家主頁地 址: 深圳福田區梅華路105號多麗工業區科技樓605 聯系人: Miss Yao 電 話: 0755-26755892(深圳) 010-88594029(北京) 021-34613729(上海) 020-87615159 (廣州) 傳 真: 0755-26755877 Email:market@neobioscience.com 相關咨詢TrailBlazer Tag and StarBright Dye Label Kits常見問題解答 (暫無發布時間 瀏覽數:5181) 人工miRNA:降低 SNCA 的新策略,或為α?突觸核蛋白病帶來突破 (暫無發布時間 瀏覽數:5664) 可靠的細胞因子,顛覆性突破! (暫無發布時間 瀏覽數:10086) IHC實驗高效秘籍之—如何制備高質量樣本? (暫無發布時間 瀏覽數:8584) 小細胞肺癌中神經內分泌–簇狀細胞譜系可塑性的最新進展 (暫無發布時間 瀏覽數:8903) 增強星形膠質細胞介導的 β?淀粉樣蛋白清除:阿爾茨海默病研究的新方向 (暫無發布時間 瀏覽數:9659) 欣博盛成為Mabtech EYRAplex多因子檢測試劑盒流式應用領域 中國區獨家代理商 (暫無發布時間 瀏覽數:11122) GeneTex原廠指定欣博盛生物科技有限公司獨家販賣聲明 (暫無發布時間 瀏覽數:8956) EpiCypher新品:重磅推出H3K36me2抗體(貨號13-0056 ) (暫無發布時間 瀏覽數:12149) StressMarq新品:Alpha Synuclein Oligomer ELISA Kit精準檢測α-突觸核蛋白寡聚體 (暫無發布時間 瀏覽數:9123) ADVERTISEMENT
|
