Heterotrimeric G proteins are essential cellular signal transducers. Gα12 is a member of the G12/13 subfamily of G proteins. Biochemical and physiological functions of Gα12 are be

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Arf-like protein 1 (Arl1) is a member of the Arf family of regulatory GTPases

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Heterotrimeric G proteins are critical cellular signal transducers. Gαz belongs to the Gi sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other bi

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Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and surv

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ARF6 (ADP-ribosylation factor 6) is a member of the ARF super-family.

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Small GTPases are a super-family of cellular signaling regulators.

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Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene. It phosphoryla

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F-box/WD repeat-containing protein 7 is a protein that in humans is encoded by the FBXW7 gene. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase c

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BAG family molecular chaperone regulator 1 is a protein that is encoded by the BAG1 gene. It binds to oncogene BCL2, by which enhances the anti-apoptotic effects of BCL2 and repre

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EK1 (also known as extracellular signal-regulated kinases

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