
獲獎文章題目:Cuprous oxide nanoparticles inhibit the growth of cervical carcinoma by inducing autophagy.
摘要:Cervical carcinoma is one of the main causes of women’s cancer, and substantial side effects from standard treatment including platinum-based chemotherapy limit the options for escalation. In this paper, using cervical cancer cell lines and tumor-bearing mice as models, we report that CONPs could inhibit the proliferation of cancer cells in vitro and in vivo. Especially CONPs could inhibit tumor growth as cisplatin without weight loss. CONPs could also induce autophagy through AKT/mTOR pathway, which demonstrates that CONPs has the potential clinical applications.
聯科試劑:Apoptosis assay was performed using an AnnexinV-FITC/PI Apoptosis Detection Kit (Multi Sciences (Lianke) Biotech Co.,
Ltd., Hangzhou, China) by flow cytometry according to the protocol provided.
Cell cycle assay was assessed by flow cytometry using a cell cycle staining Kit (Multi Sciences (Lianke) Biotech Co., Ltd., Hangzhou,
China) according to the protocol provided.
期刊:oncotarget(影響因子5.168)
單位:上海第二軍醫大學—長海醫院
評價:本實驗室長期購買并使用聯科生物的試劑盒及相關輔助產品,該產品質量無問題,性價比高,是一款不錯的國產生物試劑,值得推薦。
