祝賀長海醫院夏蕾蕾 獲得「聯科生物論文獎勵」-商家動態-資訊-生物在線

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祝賀長海醫院夏蕾蕾 獲得「聯科生物論文獎勵」

作者:杭州聯科生物技術股份有限公司 2017-11-07T10:44 (訪問量:4978)


祝賀長海醫院夏蕾蕾 獲得「聯科生物論文獎勵」


獲獎文章題目:Cuprous oxide nanoparticles inhibit the growth of cervical carcinoma by inducing autophagy.


摘要:Cervical carcinoma is one of the main causes of women’s cancer, and substantial side effects from standard treatment including platinum-based chemotherapy limit the options for escalation. In this paper, using cervical cancer cell lines and tumor-bearing mice as models, we report that CONPs could inhibit the proliferation of cancer cells in vitro and in vivo. Especially CONPs could inhibit tumor growth as cisplatin without weight loss. CONPs could also induce autophagy through AKT/mTOR pathway, which demonstrates that CONPs has the potential clinical applications.


聯科試劑:Apoptosis assay was performed using an AnnexinV-FITC/PI Apoptosis Detection Kit (Multi Sciences (Lianke) Biotech Co.,
Ltd., Hangzhou, China
) by flow cytometry according to the protocol provided.
Cell cycle assay was assessed by flow cytometry using a cell cycle staining Kit (
Multi Sciences (Lianke) Biotech Co., Ltd., Hangzhou,
China
) according to the protocol provided.


期刊:oncotarget(影響因子5.168)


單位:上海第二軍醫大學—長海醫院


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