新型冠狀病毒科研試劑
為了支持武漢新型冠狀病毒相關研究和治療產品開發，安必奇生物成立了專項工作小組，開展新型冠狀病毒的研究。我們很快拿到了病毒基因序列信息，并研發生產出新型冠狀病毒主要受體-ACE2蛋白產品，用于新型冠狀病毒科學研究。
ACE2蛋白產品：
- ACE2-239H (Fc region of human IgG1)
- ACE2-185H (Fc region of mouse IgG1)
- ACE2-736H
同時，我們正在積極制備2019-nCoV S1蛋白，屆時可與ACE2蛋白配套供應。我們密切關注新型冠狀病毒研究動態，逐步提供更多科研試劑滿足新型冠狀病毒研究。
產品信息：
|
產品名稱 |
Recombinant Human ACE2, Fc tagged |
|
貨號 |
ACE2-239H |
|
產品信息 |
Recombinant Human ACE2 extracellular domain precursor (Met 1-Ser 740) (NP_068576.1), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell. |
|
來源 |
Human cells |
|
成分 |
Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5 |
|
分子量 |
The recombinant human ACE2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 961 amino acids and predicts a molecular mass of 110.3 kDa. As a result of glycosylation, the rhACE2/Fc monomer migrates as approximately 145-150 kDa band in SDS-PAGE under reducing conditions. |
|
內毒素 |
< 1.0 eu per μg of the protein as determined by the LAL method |
|
純度 |
>90 % as determined by SDS-PAGE |
|
產品名稱 |
Recombinant Human ACE2 Protein, Fc-tagged |
|
貨號 |
ACE2-185H |
|
產品信息 |
Recombinant human ACE2 (NP_068576.1) (Met1-Ser740) was expressed with the Fc region of mouse IgG1 at the C-terminus. |
|
來源 |
HEK293 |
|
成分 |
Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol |
|
分子量 |
The recombinant human ACE2 consists 957 amino acids and predicts a molecular mass of 110 kDa. |
|
內毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method |
|
純度 |
>90 % as determined by SDS-PAGE |
|
產品名稱 |
Recombinant Human ACE2, His-tagged |
|
貨號 |
ACE2-736H |
|
產品信息 |
Recombinant human ACE-2 produced by transfected human cells is a secreted protein with sequence (Gln18-Ser740) of human ACE-2 fused with a polyhistidine tag at the C-terminus. |
|
來源 |
HEK293 |
|
成分 |
Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.1mM ZnCl2, 10% Glycerol, pH 7.5 |
|
生物活性 |
Specific Activity is > 800 pmol/min/μg as measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH |
|
內毒素 |
Less than 0.1 ng/μg (1 IEU/μg) |
|
純度 |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE |